FWIW, Wikimedia moved from Florida to San Francisco precisely for the immense value of being at the centre of things instead of the middle of nowhere (and yes, Tampa is the middle of nowhere for these purposes, even though it still has the primary data centre). Even paying local charity scale rather than commercial scale (there's a sort of cycle where WMF hires brilliant kids, they do a few years working at charity scale then go to Facebook/Google/etc for gobs of cash), being in the centre of things gets them staff and contacts they just couldn't get if they were still in Tampa. And yes, the question came up there pretty much the same as it's coming up here: why be there instead of remote? Because so much comes with being where things are actually happening, even if it doesn't look directly related to your mission (educational charity, AI research institute).