Broadly speaking, I agree with Holden, although possibly not his specific arguments. I'm not convinced that AI will appear in the manner SI postulates, and I have no real reason to believe that they will have an impact on existential probabilities. Similarly, I don't believe that donating to CND helped overt nuclear war.

Given that there are effective charities available which can make an immediate difference to people's lives, I would argue that concerned individuals should donate to those.