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Jayson_Virissimo comments on Food4Me - personalised nutrition initiative - Less Wrong
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Yeah, I have the GG genotype of rs1801282 (also known as the Pro12Ala variant in the PPARG gene) too, so 23andme tells me that "a diet high in monounsaturated fat is not likely to have beneficial effects on BMI or waist circumference." On the other hand, shortly after adopting a high-fat diet my weight dropped dramatically.
I have GG there too, which threw me for a loop because I'd been going in a paleo direction. I haven't had any dramatic effects, but I haven't been all that consistent except for blending MCT into my morning coffee. Good to hear rs1801282 isn't the last word on high-fat diets.
Coffee is pretty much ambrosia as far as I am concerned. I have a cup of coffee with grass-fed organic butter, low-carb protein powder, coconut oil, chia seeds, and creatine almost everyday.