nyan_sandwich comments on One possible issue with radically increased lifespan - Less Wrong
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Stinky motivated stopping. Birth rates aren't the only problem. Personal growth causes the same problem.
Agree about not actually needing to address this yet. our future selves will be much smarter and still have plenty of time.
Speed of light latency puts limits on the maximum size of a brain. Or, rather, it enforces a relationship between the speed of operation of a brain and its size. At a certain point, making a sphere of computronium bigger no longer makes it more effective, since it needs to talk to working components that are physically distant. Granted, it's not a small limit, especially if people want a bunch of copies of themselves.