Honestly, I think PT:TLoS is probably best for those who already understand Bayesian statistics to a fair degree (and remember their calculus). I'm currently inching my way through Sivia's 2006 Data Analysis: A Bayesian Tutorial and hoping I'll do better with that than Jaynes.
I think PT:TLoS is probably best for those who understand frequentist statistics to a fair degree. He spends a whole load of the book arguing against them, so it helps to know what he's talking about (contrary to his recommendation that knowing no frequentist statistics will help). The Bayesian stuff he builds from the ground up, calculus is all that's needed to follow it.
Here's the new thread for posting quotes, with the usual rules: