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What do you see as the biggest practical technological application of particle physics (e.g., quarks and charms) that will come out in 4-10 years?
A few years ago, I heard about a very penetrating scanner for shipping containers, that used muons, which are second-generation particles, analogous to charm, but for leptons. I don't know whether it's still promising or not.
I don't know of any other applications for second- or third-generation particles. They all have so much shorter lifetimes than muons, it's hard to do anything with them.
The muon-based scanner is still alive - it was mentioned in a recent APS news. Apparently, it relies on cosmic ray muons only.