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Risto_Saarelma comments on Neuroscience basics for LessWrongians - Less Wrong
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I'm not sure where you're going with this. I'm not seeing anything here that would argue that the complexity of the actual Vista implementation would increase ten or a hundred-fold, just some added constant difficulties in the beginning. Hypercomputation devices might mess up the nice and simple theory, but I'm waiting for one to show up in the real world before worrying much about those. I'm also still pretty confident that human cells can't act as Turing oracles, even if they might squeeze a bit of extra computation juice from weird quantum mechanical tricks.
Mechanisms that showed up so early in evolution that all eukaryotes have them took a lot less evolutionary search than the features of human general intelligence, so I wouldn't rank them anywhere close to the difficulty of human general intelligence in design discoverability.
Organelles might not be Turing oracles, but they can compute folding problems in constant time or less. And I was trying to point out that you can't implement Vista and an x86 emulator on any other hardware for less than you can Implement Vista directly on x86 hardware.
EDIT: Considering that the evolutionary search took longer to find mitochondria from the beginning of life than it took to find intelligence from mitochondria, I think that mitochondria are harder to make from primordial soup than intelligence is to make from phytoplankton.