This is a linkpost for http://www.overcomingbias.com/2012/06/plastination-is-near.html
Need to make sure you are preserving the gates in membranes, ion channels, etc (if you don't, likely you won't be preserved). You are probably not preserving microtubules and proteins attached to them and this might matter. DNA methylation and proteins attached to DNA may also be important. I do like the approach as tissue sample preparation though.
Comments? If superior brain preservation can be demonstrated under a 5nm-resolution 3D scan, plastination wins over vitrification hands-down. Is Robin missing anything here, or is this indeed as important as he says?