I am skeptical about the more complex meta-strategies discussed in the interview. If you play a ZD strategy, but switch to a different ZD strategy if after 100 moves you're not doing as well as you should be, then you're not playing a ZD strategy: you're playing some different strategy that has a 100-move memory. The extortion arguments only go through if you set a strategy at the beginning of time and never touch it again, in which case there is no place for bargaining.
Less Wrong had a Prisoner's Dilemma contest some time back, whose results I've forgotten. Perhaps it should be rerun with William H. Press & Freeman Dyson's proposed extortionate strategies.
I hope Pinker gives a response at Edge.org, since P.D played a significant role his book "The Better Angels of Our Nature" as a source of morality embedded in the nature of logic/reality.
Hat-tip to Marginal Revolution.