gwern comments on Open Thread, July 1-15, 2012 - Less Wrong
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Can anyone recommend me any nootropics for raising concentration (executive functions, working memory) that are effective, legal in the UK, not too expensive, and without too much side effects? My concentration is quite bad, if that's relevant.
What do you make of nicotine?
I suppose the risk of addiction is lower if it's taken in a non-inhaled form, but it's far from zero.
A good datapoint, thanks. I'll have to read it thoroughly later.
(I'm not sure how important it is - if there is no transition to tobacco use, which was my principal concern from the start, is it really a problem? I know for a fact that I am addicted to caffeine and anyone who starts using caffeine will quite likely become addicted, but does that really bother anyone?)
Are you addicted, or just dependent? (Many drugs cause dependence without being addictive - anything that causes withdrawal symptoms causes dependence, and caffeine does cause withdrawal symptoms.)
There are many different definitions of addiction, so if you're really curious, you might want to specify which particular set of definitions for technical terms like 'dependence' or 'addiction' you're using.
Another thing I found:
[A]n adolescent who had smoked just one cigarette at age 11 was twice as likely to be a regular smoker at age 14 than those who had not tried a cigarette at age 11. This was true even for the kids who did not smoke again in the intervening years.
Source.
(Edited to include a bigger quote.)
How can the 14 year old be considered a 'regular smoker' when he hasn't smoked in three years?
I assume those were years in which he was 11, 12, and 13?
An implied floor(age) hadn't occured to me. I suppose that means that on average the 14 year olds in question would have 0.5 years in which to become a regular smoker. An... interesting... thing to measure. The ones that would be most likely to be smokers would then be those that are closer to 15 than 14.
That's not a very useful datapoint.
Sorry, my post kind of got messed up; the link is visible now.
I meant, first, it's about tobacco and not nicotine, and second, it's a longitudinal correlational study, not causal as your link immediately jumps to (it "creates" a vulnerability).
is not nearly enough to claim you have screened off all possible variables and now you are entitled to infer causation. (And the claim is pretty dubious in the first claim: one cigarette does all that? Even stuff like heroin doesn't guarantee addiction after the first injection!)
Going to the full text:
If there is a causal effect, I like the social suggestion:
Perfectly consistent with a 2:1 odds-ratio, fits with the elimination of the effect by mid-teens, and doesn't attribute implausible powers to tobacco.
One cigarette causes does cause permanent, observable-on-autopsy changes in rat brains...
Such as?
::did Googling::
::retracts post::
Ha, I got the idea for nootropics from your dual n-back article in the first place.
I'll certainly try some nicotine gums, but would that be strong? I'd like something strong, like Adderall, but I know that Adderall is illegal without prescription (damn stupid laws), and I will likely never be in the state of having an ADHD diagnosis.
The Adderall I used was apparently a lower dose than some people use and I haven't tried nicotine double-blinded yet (soon though!); with those caveats, my impression has been that 2mg of nicotine is somewhat weaker than the Adderall but without the more negative side-effects of 'tweaking'.