But the problem with Intel — it was in the wrong market! — was so deep that the place to intervene was at a very low level, the foundations of the entire company.

Wouldn't this be better described as a very high level, not a very low level? You seem to adopt this mapping later on:

Or, if you're in a crippling environment like North Korea or Nigeria or Detroit, then perhaps the highest level intervention for you is to get up and move someplace better.