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Sarokrae comments on An Intuitive Explanation of Solomonoff Induction - Less Wrong
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Agree with this. Knowing the truth has a value and a cost (doing the experiment).
I recently heard something along the lines of: "We don't have proof that antihistamines work to treat anaphylaxis, because we haven't done the study. But the reason we haven't done the study is because we're pretty sure the control group would die."