Risto_Saarelma comments on Work on Security Instead of Friendliness? - Less Wrong
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A lot of people here think that the quick assumption that unusual substrate changes necessarily imply death isn't well-founded. Arguing with the assumption that it is obviously true will not be helpful.
There should be a good single post or wiki page to like to about this debate (it also comes up constantly in cryonics discussions), but I don't think there is one.