The idea is that there is a conserved amount of reality-stuff, and each time the world branches, the branches are thinner; they individually contain less reality-stuff than previous generations. You value a branch according to the state of the world in that branch, but then you give a weight to that branch in your calculations which depends on its thickness. This is analogous with expected utility calculations in which utility and probability enter as separate factors, except that "amount of reality-stuff" replaces probability.
One way this would make sense is if "amount of reality-stuff" was simply "number of copies of that world". Then you would be treating, and valuing, each world equally, but some worlds would be duplicated in excess of others, and so that type of world would count for more in your decision-making, not because you valued it more, but simply because it existed more often in the part of the multiverse downstream from the present moment.
Incidentally, this way of thinking would also apply to a Bohmian multiverse, in which there are no splitting worlds, but in which the Bohmian histories sometimes converge and sometimes diverge (that is, while always remaining separate self-contained worlds, sometimes they approach each other in configuration space, and sometimes they move apart). In this framework, the quantum probability density of a configuration would be the density with which the Bohmian histories cluster around that point in configuration space, and the wavefunction works as in the Copenhagen interpretation, it is a way for someone in an individual Bohmian world to reason under uncertainty. (Though if you chose to identify with the whole ensemble of your subjective duplicates throughout the Bohmian multiverse, you could to some extent preserve the MWI perspective whereby you are causally responsible for a whole ensemble of worlds, and not just for the one that this instance of you inhabits.)
One indication that "conservation of reality-stuff" may be the right principle, rather than "worlds increasing in number all the time", is that quantum mechanics only indicates relative frequencies of different outcomes. It can tell you that outcome A is twice as likely as outcome B, but it doesn't tell you the absolute number of A-worlds and B-worlds. If you had a world-splitting model, you would be free to invent your own extra law of nature about how the absolute number of worlds changes over time - bearing in mind that identical worlds can merge, so the number of worlds can decrease as well as increase. So long as the relative frequencies match quantum theory, it would be impossible to tell whether an equal-probability split in two directions produced 2 worlds, 2 billion worlds, or (2 times infinity) worlds; but according to your moral calculus, this unobservable absolute number of worlds would be extremely significant.
Returning to what people actually say about MWI, there is a tendency for MWI advocates not to talk of literally duplicated worlds, but to nonetheless treat the "quantum measure" of a world in exactly the same way that you would treat the number of duplicates of a world. If one branch has greater "measure" than another branch, then there's more of it, or it's more real, or some similar phrase will be employed. The fundamental reason for this is to be able to explain why observed probabilities are not uniform. If you break up the wavefunction into a set of basis functions (that are the "worlds") and you then treat the basis functions equally, that means that each possible world exists equally and should be of equal probability. But some things happen more often than others, to a degree that is described by the measure, so people are forced to say that some worlds count for more than others.
The reason that people don't normally justify this unequal treatment, as due to unequal numbers of duplicates being produced at branchings, is that the wavefunction contains no such phenomenon. You could postulate that the ontologically correct decomposition of the wavefunction into individual worlds always assigns equal amounts of measure to all the individual worlds, but this would involve postulating extra structure in the theory, which MWI advocates are loath to do.
Personally I find MWI advocates to be shockingly indifferent to the details of how worlds split. If the notion of world is to be taken seriously, it ought to be a mathematically exact notion. They could look for turning points (in the calculus sense) in the wavefunction, in order to identify objective boundaries and objective transitions from one world to two, e.g. when one local minimum splits into two, but once again, no-one ever follows that line of inquiry. In general, the many-worlds interpretation has a similar psychological function to the Copenhagen interpretation, namely, it's a fuzzy concept that sounds like it might make sense, so it allows users of quantum mechanics to get on with their lives and not worry about foundations. And so whole decades can pass without physicists being forced to confront the question of what the state of the unobserved electron is, or of exactly when it is that one world becomes two.
Personally I find MWI advocates to be shockingly indifferent to the details of how worlds split. If the notion of world is to be taken seriously, it ought to be a mathematically exact notion.
This might be nice, but we have to deal with what's actually the case. Wave packets simply don't divide into two at one exact instant. And if "it all adds up to normality" its not clear what use there is in introducing an arbitrary definition that allows you to say that a wave function represents one world at time t and two worlds at time t+epsilon. Whate...
If you believe the MWI [1] you should care about the future a lot more than the present. Imagine you're considering whether to take a break and eat some chocolate in an hour or in two. You'll get similar enjoyment out of both choices, so you might think it doesn't matter. But if every quantum event between one and two hours from now will branch the universe, and there are lots of such events, in two hours there would be hugely many more yous to experience your chocolate break than in only one hour. The MWI implies we should be willing to make substantial sacrifices in terms of current happiness for the benefit of our future selves. In other words, your preference for investing probably isn't strong enough.
In trying to apply this to altruism you do need to be careful. Some charities are more like spending, in that their benefits are mostly in the present, while others are like investing. If I donate to the Against Malaria Foundation to distribute mosquito nets, the main benefits are preventing current or near-future people from dying. There are probably some long term effects, like a stronger economy when you have fewer people sick, but they're not the goal or the main effect. On the other hand the Future of Humanity Institute, a charity trying to prevent existential risk, is much more like an investment in that nearly all its benefit (which is really hard to predict or quantify) goes to future people. Metacharities promoting effective altruism, like 80,000 hours, Giving What We Can, and GiveWell, are another sort of investment-like charity, influencing people's future giving. And then there's the option of straight up monetary investing now and donating later.
If you accept the MWI you should be evaluating your altruistic options primarily on their future effects, with more emphasis on farther-future ones.
I also posted this on my blog
[1] Which I still don't know enough about to have an opinion on the truth of.