But I would choose one broken leg, if that would mean that the total amount of two broken legs would go to zero then.

Creatures somewhere in existence are going to face death and severe harm for the foreseeable future. This view then seems inert.

In another words. I would vaccinate everybody (the vaccination causes discomfort) to eliminate a deadly disease like Ebola which kills few.

What would you do?

There are enough minor threats with expensive countermeasures (more expensive as higher reliability is demanded) that this approach would devour all available wealth. It would bar us from, e.g. traveling for entertainment (risk of death exists whether we walk, drive, or fly). I wouldn't want that tradeoff for society or for myself.