I guess I should articulate my confusion better: what's wrong with gradually becoming an Egan's jewelhead (sounds like an equivalent of uploading to me) or growing an earring-based prosthetic neocortex?
I don't think those outcomes would be particularly bad: they're still keeping most constraints in place. If all that remained of humanity were replicators who only cared about making more copies of themselves and might not even be conscious, now that sounds much worse.
If all that remained of humanity were mere replicators who only cared about making more copies of themselves and might not even be conscious
Adopting a somewhat external view: would not an alien looking at the earthlings describe them exactly like that?
Related to: Kaj Sotala's Posts, Blogs by LWers
By fellow LessWronger Kaj_Sotala on his blog.