Yes, and this isn't necessarily due to naive 'no mere simulation could feel so real'-type thinking either. Once can make a decent argument that the only known method of making a simulation that can fool modern physics labs would be to simulate the entire planet and much of surrounding space at the level of quantum mechanics, which is computationally intractable even with mature nanotech. Well, that or have an SI constantly tinkering with everyone's perceptions to make them think everything looks correct, but then you have to suppose that such entities have nothing more interesting to do with their runtime.