I would expect considerable differences in effectiveness among charities to remain. Even after these social and economic effects are taken into account, donating to charities that save lives in rich countries will either still be worth significantly less, per dollar donated, than saving lives in poor countries, or it will be worth significantly more. It would be surprising if the innate human tendency to favour the near and dear, which disregards causal information about how the economy and society operate, could produce results equal or very similar to those that a rational, impartial donor would want to produce.