may significantly reduce the x-risk posed by many other x-risk categories (bioengineered threats, catastrophic climate change, global nuclear catastrophe, grey goo scenarios, etcetera)
Wouldn't Earth after catastrophic climate change or global nuclear war be still more livable than Mars? If we are OK with living in shielded colonies with artificial atmosphere and controlled climate, why not build them on Earth? We wouldn't suffer from low gravity here.
If we consider malicious actions (like a big war), such colonies on Earth are just too convenient for military installations to be left untouched.
Mars colony is too far away to be able to deal a sneak attack; so wiping it is not as urgent, and after 3 hours there are no rockets anywhere on Earth for next 5 years.
Also, I am not sure that the cheapest way to "filter CO2 and CO, boost O2" is more expensive than "filter all possible chemical weapons and kill all designer bacteria".
Whether a war that realy destroys every human (maybe not ...
Article on space.com