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CellBioGuy comments on Boring Advice Repository - Less Wrong
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Nicotine does seem to activate a lot of the neurologically-controlled anti-inflammatory reflexes (while also indiscriminately poking at all the other autonomic reflexes that use the same neurotransmitters connected up to different fibers, thus the vasoconstriction and the like). Hence smokers not getting inflammitory bowel disease. I do think there are probably better methods of getting it in you than inhaling burned leaves, though perhaps not cheaper.
I semi-regularly drink vaping nicotine (aka "e-liquid") diluted in water. It is extremely cheap. I obtained 60ml of 25mg/ml strength nicotine for $10 online. It comes diluted in either vegetable glycerin or propylene glycol. A cigarette delivers around 1mg, so I usually dilute to 1-2mg in a full glass of water. To get this dose I first use a 1mg dropper to deliver 2mg of the solution to 50ml (approx. 1/2 cup) of water measured with a Pyrex glassware measuring cup. I then use the 1ml dropper to add doses of this 1mg/ml solution to a glass of water.
At 60x25=1500 cigarette-equivalent doses with no need to inhale smoke, I think "inexpensive" is an understatement. It also appears to be safe (water, nicotine, and tiny amounts of VG or PG).