This strikes me as an extremely bad idea. Regardless of your stance on whether or not humor is irrational (this is to some extent an open question), the social benefits of humor are so obvious and significant that this seems extremely unlikely to be +EV even assuming there aren't any undesirable side effects.
There may perhaps be benefits in deconditioning certain types of humor (being a wiseass, for instance), but even then I would be very, very careful and read up a lot before trying anything.
Thus spake Eliezer:
It seems that many here might have outlandish ideas for ways of improving our lives. For instance, a recent post advocated installing really bright lights as a way to boost alertness and productivity. We should not adopt such hacks into our dogma until we're pretty sure they work; however, one way of knowing whether a crazy idea works is to try implementing it, and you may have more ideas than you're planning to implement.
So: please post all such lifehack ideas! Even if you haven't tried them, even if they seem unlikely to work. Post them separately, unless some other way would be more appropriate. If you've tried some idea and it hasn't worked, it would be useful to post that too.