jamesf comments on Avoiding the emergency room - Less Wrong
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I think the main sin of Objectivism is that, though most Objectivists don't really think of it as a closed belief system, they focus too much on the writings of Ayn Rand, who for reasons of both insufficient rationality and insufficient available evidence, believed a lot of things that are now generally thought to be false (humanity's "state of nature" probably the most relevant and fundamental thing she was wrong about).