Locaha comments on After critical event W happens, they still won't believe you - Less Wrong
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The point was, Pharma is spending enormous sums of money trying to fight individual diseases (and failing like 90% of the time), and people are proposing a Manhattan project to do something far more ambitious. But a Manhattan project is in the same order of magnitude as an individual drug. IOW, a Manhattan project won't be enough.
In any case, 3 years of additional life to a mouse won't be enough, because people can always claim that the intervention is not proportional to life span. What will do the trick is an immortalized mouse, as young at 15 years as it was at 0.5.