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Eugine_Nier comments on Harry Potter and the Methods of Rationality discussion thread, part 19, chapter 88-89 - Less Wrong
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Don't werewolves have the "go psychopath once a month" problem?
Nothing to do with psychopaths, but regardless: it is predictable, medically treatable in canon, and also easily neutralized by ordinary mechanisms of confinement. If that were a method of immortality, I'd do it in a heartbeat.
If you ran the numbers, would regeneration from injury at the cost of losing human thought for three days a month* actually be worth it for most people? So far as I know, being a werewolf doesn't help with aging. I'm not sure if there's a default for whether it helps with illness.
*more or less. I think that some versions only become wolves at night.
I did say it'd be a complete no-brainer for immortality, but if we rule that out...
In HP it's just one night, IIRC (discussed in Azkaban). Regeneration from injury is probably not worth sacrificing 1/60th of a life (month has 30 days, you lose a night from a day, hence 1/60), but it is probably worth chugging the wolfsbane potion depending on costs. If being a werewolf fended against generic disease, not just injury, then it'd resume being a complete nobrainer.
What Nancy said. Also given Moody's paranoia, being dependent on something so easy to sabotage for one day a month is a huge downside.