I think that would be hard for a human to do, even if ex ante they might wish to reprogram themselves to do so.
I think it's hard because most human's don't live their lives according to principles. They care more about the lives of close friends than they care about their principles.
In the end reprograming yourself in that way is about being a good stoic.
I have sympathy with both one-boxers and two-boxers in Newcomb's problem. Contrary to this, however, many people on Less Wrong seem to be staunch and confident one-boxers. So I'm turning to you guys to ask for help figuring out whether I should be a staunch one-boxer too. Below is an imaginary dialogue setting out my understanding of the arguments normally advanced on LW for one-boxing and I was hoping to get help filling in the details and extending this argument so that I (and anyone else who is uncertain about the issue) can develop an understanding of the strongest arguments for one-boxing.