New article on in vitro iterated embryo selection

CarlShulman

The article by Robert Sparrow:

A series of recent scientific results suggest that, in the not-too-distant future, it will be possible to create viable human gametes from human stem cells. This paper discusses the potential of this technology to make possible what I call ‘in vitro eugenics’: the deliberate breeding of human beings in vitro by fusing sperm and egg derived from different stem-cell lines to create an embryo and then deriving new gametes from stem cells derived from that embryo. Repeated iterations of this process would allow scientists to proceed through multiple human generations in the laboratory. In vitro eugenics might be used to study the heredity of genetic disorders and to produce cell lines of a desired character for medical applications. More controversially, it might also function as a powerful technology of ‘human enhancement’ by allowing researchers to use all the techniques of selective breeding to produce individuals with a desired genotype.

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However, to my knowledge, the current paper is the first to explicitly discuss the possibility of the iterative use of this technology for reproductive purposes

The possibility was discussed in MIRI's "Uncertain Future" toy forecasting model back in 2009, and the analysis formulated a few years before that.

ETA: And further discussed in James Miller's recent book, "Singularity Rising."

The article by Robert Sparrow:

A series of recent scientific results suggest that, in the not-too-distant future, it will be possible to create viable human gametes from human stem cells. This paper discusses the potential of this technology to make possible what I call ‘in vitro eugenics’: the deliberate breeding of human beings in vitro by fusing sperm and egg derived from different stem-cell lines to create an embryo and then deriving new gametes from stem cells derived from that embryo. Repeated iterations of this process would allow scientists to proceed through multiple human generations in the laboratory. In vitro eugenics might be used to study the heredity of genetic disorders and to produce cell lines of a desired character for medical applications. More controversially, it might also function as a powerful technology of ‘human enhancement’ by allowing researchers to use all the techniques of selective breeding to produce individuals with a desired genotype.

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However, to my knowledge, the current paper is the first to explicitly discuss the possibility of the iterative use of this technology for reproductive purposes

Also, I'm curious if someone has an (independent) answer for the questions I posed Randall Parker in this reply, especially the last one:

http://www.futurepundit.com/archives/009032.html#reply20130803061511

Alexander, probably you could select for intelligence, using the data from the Rietveld et al study. But if you made 10 embryos and picked the one with the highest predicted IQ the increase in average offspring IQ would be under (at most, if one assumed the Rietveld results were fully solid) 3 points. And since the process has not yet been routinized, you would have to undertake serious legwork, bringing together techniques from different labs. And note that the Rietveld results are only a few months old.

But bigger genetic studies should multiply the impact of embryo selection by at least several fold over the decade.

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New article on in vitro iterated embryo selection

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New article on in vitro iterated embryo selection

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