Lumifer comments on Genies and Wishes in the context of computer science - Less Wrong

15 Post author: private_messaging 30 August 2013 12:43PM

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Comment author: Lumifer 30 August 2013 06:17:46PM 0 points [-]

I don't think that the statement

we do have chemistry figured out very well

is consistent with

it is very difficult to find the consequences of our interventions

Otherwise,

generating most plausible hypotheses that fit the data is also an optimization problem

Is not true. In your example of evolution it's sexual reproduction and mutation that "generate hypotheses" -- neither is an optimizer.

Yes, I understand that you can treat hypothesis generation as a traversal of hypothesis space and so a search and so an optimization, but that doesn't seem to be a helpful approach in this instance.

Comment author: private_messaging 30 August 2013 06:29:58PM *  1 point [-]

We have chemistry figured out, we don't have "making truly enormous computers to compute enough of that chemistry fast enough" figured out, or "computing chemistry a lot more efficiently" figured out. Does that make it clearer?

I am not entirely clear how do you imagine hypothesis generation happening on a computer, other than by either trying what sticks, or analytically finding the best hypothesis that works by working backwards from the data.

Comment author: Lumifer 30 August 2013 06:45:38PM 1 point [-]

Your position is clear, it's just that I don't agree with it. I don't think that human biochemistry has been figured out (e.g. consider protein structure). I also think that modeling human body at the chemistry level is not a problem of insufficient computing power. It's a problem of insufficient knowledge.

Non-trivial hypothesis generation is very hard to do via software which is one of the reasons why IBM's Watson haven't produced a cure for cancer already. Humans are still useful in some roles :-/

Comment author: private_messaging 30 August 2013 07:07:43PM 1 point [-]

The structure of a protein is determined by the known laws of physics, other compounds in the solution, and protein's formula (which is a trivial translation of the genetic code for that protein). But it is very computationally expensive to simulate for a large, complicated protein. Watson is a very narrow machine that tries to pretend at answering by using a large database of answers. AFAIK it can't even do trivial new answers (what is the velocity of a rock that fell from the height of 131.5 meters? Wolfram Alpha can answer this, but it is just triggered by the keyword 'fell' and 'height')