I'd say the mistake was speaking about disastrous consequences (as a certain fact), when in reality you had little information to back this up.
The proper approach in such situation would be asking: "I heard about X. Do you think it will significantly impact Y?" And then the debate would be about the estimated impacts of X (instead of about your overconfidence).
The political aspect just makes it worse, but I think speaking about disasters in situations where you have little information would be bad even in non-political areas.
For those who haven't heard, NIH and NSF are no longer processing grants, leading to many negative downstream effects.
I've been directing my attention elsewhere lately and don't have anything informative to say about this. However, my uninformed intuition is that people who care about effective altruism (research in general, infrastructure development, X-risk mitigation, life-extension...basically everything, actually) or have transhumanist leanings should be very concerned.
The consequences have already been pretty disastrous. To provide just one, immediate example, the article says that the Center for Disease Control and Prevention has shut down. I think that this is almost certain to directly cause a nontrivial number of deaths. Each additional day that this continues could have huge negative impact down the line, perhaps delaying some key future discoveries by years. This event *might* be a small window of opportunity to prevent a lot of harm very cheaply.
So the question is:
1) Can we do anything to remedy the situation?
2) If so, is it worth doing it? (Opportunity costs, etc)