This seems like a nitpick more than a serious remark: obviously one is talking about the true discoveries, and giving major examples of them in biology is not at all difficult. The discovery of RNA interference is in the biochem end of things, while a great number of discoveries have occurred in paleontology as well as using genetics to trace population migrations (both humans and non-humans).

it's normally hard to independently verify the truth of novel discoveries except in cases where those discoveries have applications.

So one question here is, for what types of discoveries is your prior high that the discovery is bogus? And how will you tell? General skepticism probably makes sense for a lot of medical "breakthroughs" but there's a lot of biology other than those.