It's an exaggeration, but not far off. The information seems pretty damn fragile. From the linked thread: "The damage that is occurring - distortion of membranes, denaturation of proteins (very likely), disruption of signalling pathways. Just changing the exact localization of Ca microdomains within a synapse can wreak havoc, replacing the liquid completely? Not going to work."
The counterarguments appear to be "but do we really need all that detail for a good-enough copy of the person?" Which is a "prove my negative" - the people arguing that don't know either.
It's a double-edged negative... not only do we not know how good the copy will be, we don't know how good is good enough. (Of course, if our standards for "good enough" are sufficiently low, then they can be satisfied by other people being born.)
Ultimately the cryonics argument is that the value to me of someone who meets my standards for being me existing in the future is so high that any increase, however small, in the chance of that happening has a higher expected value than anything else I could do with the resources consumed by post-mortem c...
In the past, the Cryonics Institute has had a policy that said that they would not accept anyone who is not a member. This has changed. The policy now is that someone who has full legal authority over your body can sign you up after you die. It costs $36,250 to be frozen if you are not signed up, which is more expensive. They also will not do anything until you have been on dry ice for 2 weeks after they have been contacted, so not being a member is more risky.
This is very important news for anyone who is currently cryocrastinating. It means that you can drastically increase your chances of survival without filling out any forms. All you have to do is tell a loved one you want to be frozen upon death, and that you would like them to take responsibility for making sure this happens. This takes literally 30 seconds. Do it now!
This news might also be a reason to not sign up right away, if you think something better (like radical life extension or uploading) will come along in your lifetime. We should discuss this in the comments.
Edit: The general consensus of this discussion is that this is a really bad reason not to sign up for cryonics.