Comment on Open Thread, October 7 - October 12, 2013

Tue, 08 Oct 2013 20:24:29 GMT

It doesn't appear to do that.:

In regards to supplementation, oral melatonin supplements at 500mcg over a period of a week in shift workers did not influence basal secretion, as cessation for one day prior to measurements did not show differences when compared to secretion status prior to supplementation.[24] 24-hour melatonin levels in this study, when graphed, essentially overlapped suggesting next to no variance.[24] These results indicating a lack of negative feedback have been replicated with 2mg[25] and 5mg.[26]

Good question! This is definitely an important thing to consider.

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