I'd extend Eugene's reply and point out that both the original and modified version of the sentence are observations. As such, it doesn't matter that the two sentences are grammatically similar; it's entirely possible that one is observed and the other is not. History has plenty of examples of people who are willing to do harm for a good cause and end up just doing harm; history does not have plenty of examples of people who are willing to cut people open to remove cancer and end up just cutting people open.
Also, the phrasing "to end malaria" isn't analogous to "to remove cancer" because while the surgery only has a certain probability of working, the uncertainty in that probability is limited. We know the risks of surgery, we know how well surgery works to treat cancer, and so we can weigh those probabilities. When ending malaria (in this example), the claim that the experiment has so-and-so chance of ending malaria involves a lot more human judgment than the claim that surgery has so-and-so chance of removing cancer.
History has plenty of examples of people who are willing to do harm for a good cause and end up just doing harm.
Yes, but keep in mind the danger of availability bias; when people are willing to do harm for a good cause, and end up doing more good than harm, we're not so likely to hear about it. Knut Haukelid and his partners caused the death of eighteen civilians, and may thereby have saved several orders of magnitude more. How many people have heard of him? But failed acts of pragmatism become scandals.
Also, some people (such as Hitler and Stalin) are ...
Another month has passed and here is a new rationality quotes thread. The usual rules are: