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Yosarian2 comments on Measuring lethality in reduced expected heartbeats - Less Wrong
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Not necessarily; more likely, it just means that damage is cumulative over time. Most people don't start smoking when they're 45, so it's not really a direct comparison.
Also, smoking seems to negatively affect brain health as well, which is problematic since reversing brain degradation might be harder then other types of anti-aging technology.