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turchin comments on [Link] Valproic acid, a drug for brain plasticity - Less Wrong
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http://en.wikipedia.org/wiki/Valproic_acid
The foremost and most severe concern for anyone taking valproic acid is its potential for sudden and severe, possibly fatal, fulminating impairments in liver and impairments of hematopoietic or pancreatic function, especially in those just starting the medication. This particular warning is the first one listed on any drug adverse effect listing when one receives the drug at the pharmacy.
Yeah, messing with valproate as a mind-hack is a potentially Darwinian endeavour. It's nasty shit in many ways, i.e. it's medicine that people don't take without a clear need and regular medical monitoring, and is not to be fooled with.