Any kind of formative skill development. Adults are great (or can be) at learning new applications of those skills, but not so much at forming entirely new skills. Look at children learning motor skills verses stroke patients, for example.
Do you have a reference discussing the comparison between children and stroke patients?
NPR reports on a study giving volprioc acid to adults and training them on pitch (singing):
Brain plasticity is useful for a whole lot more than learning pitch. As the article notes it would be invaluable for training one's ear to pick up sounds of foreign languages, but also it seems reasonable to this commentator that high levels of plasticity during rationality training or other forms of self-development would result in more transformative results.