jsalvatier comments on Literature-review on cognitive effects of modafinil (my bachelor thesis) - Less Wrong

33 Post author: wallowinmaya 08 January 2014 07:23PM

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Comment author: gwern 31 January 2014 11:15:28PM 0 points [-]

I'm curious if you have ideas on how to deal with that.

The standard solution seems to be 'multivariate meta-analysis'. I've done a little reading on the topic, but I've had trouble getting started with it - you need to know the correlations between the multiple outcome variables, this is typically unavailable (the data-sharing problem), and I think it only works anyway if there is at least a little bit of correlation between the multiple outcomes, while I would like to be able to collectively analyze outcomes from disjoint studies which is... less clear how to do.

Comment author: jsalvatier 03 February 2014 06:02:48AM 0 points [-]

Right that makes sense. People rarely report the covariance matrix of the data.

Comment author: gwern 03 February 2014 03:41:38PM 0 points [-]

Much less provide IPD/individual-patient-data which is what one really wants. The lack of data is frustrating.

Comment author: jsalvatier 05 February 2014 08:14:26PM 0 points [-]

Indeed.