Eugine_Nier comments on Rationalists Are Less Credulous But Better At Taking Ideas Seriously - Less Wrong
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There's lots of modafinil info at gwern's page. Wikipedia is also a pretty good source. The short (and only slightly inaccurate) version is that it gives you the good effects of caffeine, but stronger, and with no withdrawal or other drawbacks. It's had positive effects on my mood and focus.
Reasonable! Which is why I'm taking modafinil with the advice and supervision of a licensed medical professional. If you're wary of self-medication, you might want to look into that route.
How much data is there behind this conclusion. Is it comparable to the centuries of experience we have with caffeine?
Why are you asking, instead of looking?