Manfred comments on [Link] Death, long lives, uploading - a conworlding perspective - Less Wrong
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I will be nice rather than mean, and explain why this is wrong.
We already have artificial deices that help the blind see. We can take the signals from an amputee's brain and use them to move an artificial limb. We understand how the ear works - there are different nerves for different frequencies. Artificial taste would be pretty trivial, but isn't as good without artificial smell, which seems the hardest of all the senses. To assume that a brain simulated on a computer in 100 years won't be able to hear, touch, taste, or smell is incredibly naive about the workings of the human body and the progress that's being made right now.
Not to mention that all of your parts that can be cut off without making you stop being you, like eyes or limbs, might already best be viewed as squishy prosthetics instead of fundamental parts of your true being. Ari Heljakka has written about this stuff, unfortunately in Finnish. I wonder if his Model Zero book has something about it.