As a model, look at expat communities in e.g. China, where people who are willing living in a strange environment get the relief of sitting down and relaxing with people who have a shared cultural background. If the cryonics thing works out, I wouldn't be surprised if Alcor clients became a very tight-knit social group in the far future.
It's an idea which hasn't been used in science fiction as much as I think it deserves. Offhand, the only example I can think of is "The Flowered Thundermug" by Alfred Bester.
Death, long lives, uploading
Mark Rosenfelder (aka zompist, of language construction kit fame) writes about the advantages and drawbacks of mortality and its alternatives, in fiction and real life. Rosenfelder, as an author, clearly takes Fun Theory very seriously. After discussing the mental and physical decline that age usually entail, he assumes that the most difficult to surmount of these problems will be the loss of mental flexibility and tolerance of novelty. He then uses this obstacle to offer interesting fun-theoretic arguments against uploading and cryonics:
And how he addressed the issue in his own far-future conworld: