Gwern noted in his analysis of nicotine that to overcome dependency effects, the user could cycle between different nootropics they use. For example, a three day cycle of nicotine, then caffeine, then modafanil, then repeat and start over with nicotine.

Over the course of several months, I could trial different methods of consuming nicotine, i.e., patches, e-cigarettes, and gum. I would space each of these trials out over the course of several months because I wouldn't want each of the trials to be spaced too close together, and I wouldn't want to mess with my body by consuming too much nicotine anyway. As a protection against my subjective experience being useless, I would read more of Gwern's reviews on nootropics, and perhaps consult online nootropics communities on their methods for noting how they feel. Their could be trials I could run, or ways of taking notes, which would allow me to make the information gleaned in that regard more useful.