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RomeoStevens comments on Lifestyle interventions to increase longevity - Less Wrong
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Examine.com is much less positive about CoQ10 writing "all the noticeable effects (more vitality) could potentially be placebo. It is very much a faith buy and the costs if you take it in the wrong manner (without a fatty transport) could be quite high financially."
mean decrease in systolic pressure over 8 studies of 16mm Hg kicks the crap out of a lot of interventions, including some prescription ones.
Are there any theories about the mechanism involved here? I've done a fair bit of Googling about this but haven't found any discussion of underlying mechanisms, only the statistics. I know that CoQ10 is critical in the metabolic cycle that produces ATP, and therefore is involved in energy production everywhere in the body; but I'm not sure how to get from that to the specific result of lowering blood pressure (rather than something more general like "feel more energetic").
The fact that blood pressure is an independent predictor of mortality would imply it affects, and is most likely affected by, a lot of metabolic processes.