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RomeoStevens comments on Ergonomics Revisited - Less Wrong
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Look at a monitor in a dark room for awhile and then turn it off. You should see strobing in your vision if you have a low refresh rate monitor. This induces eye strain more quickly.
Obviously visible strobing only indicates low refresh rate in CRTs and the rare few monitors with black frame insertion or scanning backlights. In most cases strobing is caused by PWM brightness control, which has the visual disadvantage of strobing without the sample-and-hold-blur reducing advantage of frame-syncronized strobing. PWM brightness control is purely a cost saving measure. At high frequencies it might not bother you but it's rare for PWM frequency to be listed in the specifications.
My phone uses PWM brightness control at about 200Hz so I run it at full brightness (100% duty cycle) if I'm using it for a long time which negates the strobing.