The additivity may or may not hold when pushing into genius territory.
There's no a priori reason to expect additivity to suddenly fail when going outside. That's the point of additivity: if they depended on the presence or absence of other variants to have effect, then that would fall into the non-additive parts.
That's not self-evident to me for very high IQ types.
When we look at regressions for IQ, we almost always see strong positive effects going as high as we can meaningfully measure or get sample sizes. Consider the SMPY studies. I'm not aware of any results from their longitudinal results showing worse problems than your average 100 IQ schmoe. And it should be self-evident: do you associate MIT or Stanford or Harvard or Tsinghua graduates with extremely high flameout rates, shorter lifespans, lower incomes, any of that...?
the attempts to genetically engineer high IQ might find different paths in that general direction, some are likely to have serious side effects.
If there were serious common side effects from the common variants detected by current GWAS, as a statistical necessity, those variants would have been disease hits before they were intelligence hits of small effect.
There's no a priori reason to expect additivity to suddenly fail when going outside.
We just don't know at this point. On general grounds I'm suspicious of claims that in highly complex systems stochastic relationships observed for the middle of the distribution necessarily hold far into the tails. In this case I have no strong opinions on whether it will or will not hold.
MIT or Stanford or Harvard or Tsinghua graduates
By "very high IQ types" I mean geniuses. MIT, Stanford, etc. do not graduate geniuses, they graduate merely high-IQ people....
I suggested recently that part of the problem with with LW was a lock of discussion posts which was caused by people not thinking of much to post about.
When I ask myself "what might be a good topic for a post?", my mind goes blank, but surely not everything that's worth saying that's related to rationality has been said.
So, is there something at the back of your mind which might be interesting? A topic which got some discussion in an open thread that could be worth pursuing?
If you've found anything which helps you generate useable ideas, please comment about it-- or possibly write a post on the subject.