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jimrandomh comments on LINK: Blood from youth keeps you young - Less Wrong
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Before you get your hopes up, keep in mind: be warned research in mice has a very poor track record for generalizing to humans.
I don't suppose there's a highly-accessible curated database of hypotheses which appear to have tested very differently between mice (or other subjects) and humans. Suddenly this strikes me as a highly valuable resource.
Now I'm wondering if there's a way to make that the start of a viable business, but of course my pondering is limited by knowledge outside my domain.
You may find some of the reviews and meta-analyses in http://www.gwern.net/DNB%20FAQ#fn97 to be of interest!
I'm not sure about the FDA, though. IIRC, they only require all human trials to be reported, and they don't release the information. (This is why the recent Tamiflu meta-analysis was such big news: because the researchers managed to force the disgorgement of all studies' data and show poor performance of Tamiflu & systematic bias in which studies got officially published.)
There's data from clinical trials. Before doing experiments with humans a company has to make the experiments in mice (or other animals). Any clinical trial of a drug that fails can be seen as a trial where a hypothesis failed to generalize. If I remember right the FDA does release some of the relevant data.