I don't suppose there's a highly-accessible curated database of hypotheses which appear to have tested very differently between mice (or other subjects) and humans. Suddenly this strikes me as a highly valuable resource.
Now I'm wondering if there's a way to make that the start of a viable business, but of course my pondering is limited by knowledge outside my domain.
I don't suppose there's a highly-accessible curated database of hypotheses which appear to have tested very differently between mice (or other subjects) and humans.
You may find some of the reviews and meta-analyses in http://www.gwern.net/DNB%20FAQ#fn97 to be of interest!
I'm not sure about the FDA, though. IIRC, they only require all human trials to be reported, and they don't release the information. (This is why the recent Tamiflu meta-analysis was such big news: because the researchers managed to force the disgorgement of all studies' data and show p...
In experiments performed on mice, blood transfusions from young mice reversed age-related markers in older mice. The protein involved is identical in humans.
http://mic.com/articles/88851/harvard-scientists-may-have-just-unlocked-the-secret-to-staying-young-forever