Houshalter comments on Evolutions Are Stupid (But Work Anyway) - Less Wrong
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Well genetic algorithms work by making assumptions about the problem space, mainly that better solutions are very likely to be found close to other good solutions. If the assumption is not true or only weakly true, than of course it isn't going to work. Like if beneficial mutations are extremely rare or practically non-existent.
My point is that it depends entirely on the problem and how it's represented. Some problems work really well for GAs, and some don't at all.