No, the difference is that con artists are another intelligence, and you are in competition. Anytime you are in competition against a better more expert intelligence, it is an important difference.

The activities of others are important data, because they are often rationally motivated. If a con artist offers me a bet, that tells me that he values his side of the bet more. If an expert investor sells a stock, they must believe the stock is worth less than some alternate investment. So when playing assume that odds are bad enough to justify their actions.