AnthonyC comments on The Octopus, the Dolphin and Us: a Great Filter tale - Less Wrong
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We can do quite a lot with light elements now, after we spent millennia figuring out metals. We still use a lot of metal equipment and catalysts in the manufacturing of polymers and carbon fiber. I'm sure there are processes for making them without metals, but getting civilization going in the first place would be much harder without elements heavier than iron.