Sure. Have you actually seen "the territory"? Of course not. There are plenty of unexplained observations out there. We assume that these come from some underlying "reality" which generates them. And it's a fair assumption. It works well in many cases. But it is still an assumption, a model. To quote Brienne Strohl on noticing:

You're unlikely to generate alternative hypotheses when the confirming observation and the favored hypothesis are one and the same in your experience of experience.

To most people the map/territory observation is such a "one and the same". I'm suggesting that it's only a hypothesis. It gives way when making a map changes the territory (hello, QM). It is also unnecessary, because the useful essence of the map/territory model is that "future is partially predictable", in a sense that it is possible to take our past experiences, meditate on it for a while, figure out what to expect in the future and see our expectations at least partially confirmed. There is no need to attach the notion of some objective reality causing this predictability, though admittedly it does feel good to pretend that we stand on a solid ground, and not on some nebulous figment of imagination.

If you extract this essence, that future experiences are predictable from the past ones, and that we can shape our future experiences based on the knowledge of the past, it is enough to do science (which is, unsurprisingly, designing, testing and refining models). There is no indication that this model building will one day be exhausted. In fact, there is plenty of evidence to the contrary. It has happened many times throughout human history that we thought that our knowledge was nearly complete, there was nothing more to discover, except for one or two small things here and there. And then those small things became gateways to more surprising observations.

Yet we persist in thinking that there are ultimate laws of the universe, and that some day we might discover them all. I posit that there are no such laws, and we will continue digging deeper and deeper, without ever reaching the bottom... because there is no bottom.