CarlShulman comments on SRG 4: Biological Cognition, BCIs, Organizations - Less Wrong

7 Post author: KatjaGrace 07 October 2014 01:00AM

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Comment author: PhilGoetz 07 October 2014 11:56:19AM *  1 point [-]

One problem is that for that approach, you would need, say, standardized IQ tests and genomes for a large number of people, and then to identify genome properties correlated with high IQ.

First, all biologists everywhere are still obsessed with "one gene" answers. Even when they use big-data tools, they use them to come up with lists of genes, each of which they say has a measurable independent contribution to whatever it is they're studying. This is looking for your keys under the lamppost. The effect of one gene allele depends on what alleles of other genes are present. But try to find anything in the literature acknowledging that. (Admittedly we have probably evolved for high independence of genes, so that we can reproduce thru sex.)

Second, as soon as you start identifying genome properties associated with IQ, you'll get accused of racism.

Comment author: CarlShulman 07 October 2014 11:32:24PM *  3 points [-]

You can deal with epistasis using the techniques Hsu discusses and big datasets, and in any case additive variance terms account for most of the heritability even without doing that. There is much more about epistasis (and why it is of secondary importance for characterizing the variation) in the linked preprint.